Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis
Identifieur interne : 000299 ( Main/Exploration ); précédent : 000298; suivant : 000300Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis
Auteurs : Florence Tatin [Royaume-Uni] ; Andrea Taddei [Royaume-Uni] ; Anne Weston [Royaume-Uni] ; Elaine Fuchs [États-Unis] ; Danelle Devenport [États-Unis] ; Fadel Tissir [Belgique] ; Taija Makinen [Royaume-Uni]Source :
- Developmental Cell [ 1534-5807 ] ; 2013.
Abstract
Planar cell polarity (PCP) signaling controls tissue morphogenesis by coordinating collective cell behaviors. We show a critical role for the core PCP proteins Celsr1 and Vangl2 in the complex morphogenetic process of intraluminal valve formation in lymphatic vessels. We found that valve-forming endothelial cells undergo elongation, reorientation, and collective migration into the vessel lumen as they initiate valve leaflet formation. During this process, Celsr1 and Vangl2 are recruited from endothelial filopodia to discrete membrane domains at cell-cell contacts.
Url:
DOI: 10.1016/j.devcel.2013.05.015
PubMed: 23792146
PubMed Central: 3714594
Affiliations:
- Belgique, Royaume-Uni, États-Unis
- New Jersey, Province du Brabant wallon, Région wallonne, État de New York
- Louvain-la-Neuve, Princeton (New Jersey)
- Université catholique de Louvain, Université de Princeton
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000357
- to stream Pmc, to step Curation: 000357
- to stream Pmc, to step Checkpoint: 000252
- to stream Ncbi, to step Merge: 000184
- to stream Ncbi, to step Curation: 000184
- to stream Ncbi, to step Checkpoint: 000184
- to stream Main, to step Merge: 000299
- to stream Main, to step Curation: 000299
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis</title><author><name sortKey="Tatin, Florence" sort="Tatin, Florence" uniqKey="Tatin F" first="Florence" last="Tatin">Florence Tatin</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Taddei, Andrea" sort="Taddei, Andrea" uniqKey="Taddei A" first="Andrea" last="Taddei">Andrea Taddei</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Weston, Anne" sort="Weston, Anne" uniqKey="Weston A" first="Anne" last="Weston">Anne Weston</name><affiliation wicri:level="1"><nlm:aff id="aff2">Electron Microscopy Unit, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Electron Microscopy Unit, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Fuchs, Elaine" sort="Fuchs, Elaine" uniqKey="Fuchs E" first="Elaine" last="Fuchs">Elaine Fuchs</name><affiliation wicri:level="2"><nlm:aff id="aff3">Laboratory of Mammalian Cell Biology and Development, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 300, New York, NY 10065, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Mammalian Cell Biology and Development, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 300, New York, NY 10065</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Devenport, Danelle" sort="Devenport, Danelle" uniqKey="Devenport D" first="Danelle" last="Devenport">Danelle Devenport</name><affiliation wicri:level="4"><nlm:aff id="aff4">Department of Molecular Biology, Princeton University, 119 Lewis Thomas Labs, Washington Road, Princeton, NJ 08544, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Princeton University, 119 Lewis Thomas Labs, Washington Road, Princeton, NJ 08544</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">Princeton (New Jersey)</settlement></placeName><orgName type="university">Université de Princeton</orgName></affiliation></author><author><name sortKey="Tissir, Fadel" sort="Tissir, Fadel" uniqKey="Tissir F" first="Fadel" last="Tissir">Fadel Tissir</name><affiliation wicri:level="4"><nlm:aff id="aff5">Institute of Neuroscience, Developmental Neurobiology, Université Catholique de Louvain, B1200 Brussels, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Institute of Neuroscience, Developmental Neurobiology, Université Catholique de Louvain, B1200 Brussels</wicri:regionArea><orgName type="university">Université catholique de Louvain</orgName><placeName><settlement type="city">Louvain-la-Neuve</settlement><region type="region" nuts="1">Région wallonne</region><region type="province" nuts="1">Province du Brabant wallon</region></placeName></affiliation></author><author><name sortKey="Makinen, Taija" sort="Makinen, Taija" uniqKey="Makinen T" first="Taija" last="Makinen">Taija Makinen</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23792146</idno><idno type="pmc">3714594</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714594</idno><idno type="RBID">PMC:3714594</idno><idno type="doi">10.1016/j.devcel.2013.05.015</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000357</idno><idno type="wicri:Area/Pmc/Curation">000357</idno><idno type="wicri:Area/Pmc/Checkpoint">000252</idno><idno type="wicri:Area/Ncbi/Merge">000184</idno><idno type="wicri:Area/Ncbi/Curation">000184</idno><idno type="wicri:Area/Ncbi/Checkpoint">000184</idno><idno type="wicri:doubleKey">1534-5807:2013:Tatin F:planar:cell:polarity</idno><idno type="wicri:Area/Main/Merge">000299</idno><idno type="wicri:Area/Main/Curation">000299</idno><idno type="wicri:Area/Main/Exploration">000299</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis</title><author><name sortKey="Tatin, Florence" sort="Tatin, Florence" uniqKey="Tatin F" first="Florence" last="Tatin">Florence Tatin</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Taddei, Andrea" sort="Taddei, Andrea" uniqKey="Taddei A" first="Andrea" last="Taddei">Andrea Taddei</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Weston, Anne" sort="Weston, Anne" uniqKey="Weston A" first="Anne" last="Weston">Anne Weston</name><affiliation wicri:level="1"><nlm:aff id="aff2">Electron Microscopy Unit, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Electron Microscopy Unit, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author><author><name sortKey="Fuchs, Elaine" sort="Fuchs, Elaine" uniqKey="Fuchs E" first="Elaine" last="Fuchs">Elaine Fuchs</name><affiliation wicri:level="2"><nlm:aff id="aff3">Laboratory of Mammalian Cell Biology and Development, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 300, New York, NY 10065, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Mammalian Cell Biology and Development, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 300, New York, NY 10065</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Devenport, Danelle" sort="Devenport, Danelle" uniqKey="Devenport D" first="Danelle" last="Devenport">Danelle Devenport</name><affiliation wicri:level="4"><nlm:aff id="aff4">Department of Molecular Biology, Princeton University, 119 Lewis Thomas Labs, Washington Road, Princeton, NJ 08544, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Princeton University, 119 Lewis Thomas Labs, Washington Road, Princeton, NJ 08544</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">Princeton (New Jersey)</settlement></placeName><orgName type="university">Université de Princeton</orgName></affiliation></author><author><name sortKey="Tissir, Fadel" sort="Tissir, Fadel" uniqKey="Tissir F" first="Fadel" last="Tissir">Fadel Tissir</name><affiliation wicri:level="4"><nlm:aff id="aff5">Institute of Neuroscience, Developmental Neurobiology, Université Catholique de Louvain, B1200 Brussels, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Institute of Neuroscience, Developmental Neurobiology, Université Catholique de Louvain, B1200 Brussels</wicri:regionArea><orgName type="university">Université catholique de Louvain</orgName><placeName><settlement type="city">Louvain-la-Neuve</settlement><region type="region" nuts="1">Région wallonne</region><region type="province" nuts="1">Province du Brabant wallon</region></placeName></affiliation></author><author><name sortKey="Makinen, Taija" sort="Makinen, Taija" uniqKey="Makinen T" first="Taija" last="Makinen">Taija Makinen</name><affiliation wicri:level="1"><nlm:aff id="aff1">Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Lymphatic Development Laboratory, Cancer Research UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3LY</wicri:regionArea><wicri:noRegion>London WC2A 3LY</wicri:noRegion></affiliation></author></analytic><series><title level="j">Developmental Cell</title><idno type="ISSN">1534-5807</idno><idno type="eISSN">1878-1551</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Planar cell polarity (PCP) signaling controls tissue morphogenesis by coordinating collective cell behaviors. We show a critical role for the core PCP proteins Celsr1 and Vangl2 in the complex morphogenetic process of intraluminal valve formation in lymphatic vessels. We found that valve-forming endothelial cells undergo elongation, reorientation, and collective migration into the vessel lumen as they initiate valve leaflet formation. During this process, Celsr1 and Vangl2 are recruited from endothelial filopodia to discrete membrane domains at cell-cell contacts. <italic>Celsr1</italic>- or <italic>Vangl2</italic>-deficient mice show valve aplasia due to failure of endothelial cells to undergo rearrangements and adopt perpendicular orientation at valve initiation sites. Mechanistically, we show that Celsr1 regulates dynamic cell movements by inhibiting stabilization of VE-cadherin and maturation of adherens junctions. These findings reveal a role for PCP signaling in regulating adherens junctions and directed cell rearrangements during vascular development.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bastock, R" uniqKey="Bastock R">R. Bastock</name></author><author><name sortKey="Strutt, D" uniqKey="Strutt D">D. Strutt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bazigou, E" uniqKey="Bazigou E">E. Bazigou</name></author><author><name sortKey="Makinen, T" uniqKey="Makinen T">T. Makinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bazigou, E" uniqKey="Bazigou E">E. Bazigou</name></author><author><name sortKey="Xie, S" uniqKey="Xie S">S. Xie</name></author><author><name sortKey="Chen, C" uniqKey="Chen C">C. Chen</name></author><author><name sortKey="Weston, A" uniqKey="Weston A">A. Weston</name></author><author><name sortKey="Miura, N" uniqKey="Miura N">N. Miura</name></author><author><name sortKey="Sorokin, L" uniqKey="Sorokin L">L. Sorokin</name></author><author><name sortKey="Adams, R" uniqKey="Adams R">R. Adams</name></author><author><name sortKey="Muro, A F" uniqKey="Muro A">A.F. Muro</name></author><author><name sortKey="Sheppard, D" uniqKey="Sheppard D">D. Sheppard</name></author><author><name sortKey="Makinen, T" uniqKey="Makinen T">T. Makinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bazigou, E" uniqKey="Bazigou E">E. Bazigou</name></author><author><name sortKey="Lyons, O T" uniqKey="Lyons O">O.T. Lyons</name></author><author><name sortKey="Smith, A" uniqKey="Smith A">A. Smith</name></author><author><name sortKey="Venn, G E" uniqKey="Venn G">G.E. Venn</name></author><author><name sortKey="Cope, C" uniqKey="Cope C">C. Cope</name></author><author><name sortKey="Brown, N A" uniqKey="Brown N">N.A. Brown</name></author><author><name sortKey="Makinen, T" uniqKey="Makinen T">T. Makinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bertet, C" uniqKey="Bertet C">C. Bertet</name></author><author><name sortKey="Sulak, L" uniqKey="Sulak L">L. Sulak</name></author><author><name sortKey="Lecuit, T" uniqKey="Lecuit T">T. Lecuit</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blum, Y" uniqKey="Blum Y">Y. Blum</name></author><author><name sortKey="Belting, H G" uniqKey="Belting H">H.G. Belting</name></author><author><name sortKey="Ellertsdottir, E" uniqKey="Ellertsdottir E">E. Ellertsdottir</name></author><author><name sortKey="Herwig, L" uniqKey="Herwig L">L. Herwig</name></author><author><name sortKey="Luders, F" uniqKey="Luders F">F. Lüders</name></author><author><name sortKey="Affolter, M" uniqKey="Affolter M">M. Affolter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bose, R" uniqKey="Bose R">R. Bose</name></author><author><name sortKey="Wrana, J L" uniqKey="Wrana J">J.L. Wrana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carreira Barbosa, F" uniqKey="Carreira Barbosa F">F. Carreira-Barbosa</name></author><author><name sortKey="Kajita, M" uniqKey="Kajita M">M. Kajita</name></author><author><name sortKey="Morel, V" uniqKey="Morel V">V. Morel</name></author><author><name sortKey="Wada, H" uniqKey="Wada H">H. Wada</name></author><author><name sortKey="Okamoto, H" uniqKey="Okamoto H">H. Okamoto</name></author><author><name sortKey="Martinez Arias, A" uniqKey="Martinez Arias A">A. Martinez Arias</name></author><author><name sortKey="Fujita, Y" uniqKey="Fujita Y">Y. Fujita</name></author><author><name sortKey="Wilson, S W" uniqKey="Wilson S">S.W. Wilson</name></author><author><name sortKey="Tada, M" uniqKey="Tada M">M. Tada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, P L" uniqKey="Chen P">P.L. Chen</name></author><author><name sortKey="Clandinin, T R" uniqKey="Clandinin T">T.R. Clandinin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ciruna, B" uniqKey="Ciruna B">B. Ciruna</name></author><author><name sortKey="Jenny, A" uniqKey="Jenny A">A. Jenny</name></author><author><name sortKey="Lee, D" uniqKey="Lee D">D. Lee</name></author><author><name sortKey="Mlodzik, M" uniqKey="Mlodzik M">M. Mlodzik</name></author><author><name sortKey="Schier, A F" uniqKey="Schier A">A.F. Schier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curtin, J A" uniqKey="Curtin J">J.A. Curtin</name></author><author><name sortKey="Quint, E" uniqKey="Quint E">E. Quint</name></author><author><name sortKey="Tsipouri, V" uniqKey="Tsipouri V">V. Tsipouri</name></author><author><name sortKey="Arkell, R M" uniqKey="Arkell R">R.M. Arkell</name></author><author><name sortKey="Cattanach, B" uniqKey="Cattanach B">B. Cattanach</name></author><author><name sortKey="Copp, A J" uniqKey="Copp A">A.J. Copp</name></author><author><name sortKey="Henderson, D J" uniqKey="Henderson D">D.J. Henderson</name></author><author><name sortKey="Spurr, N" uniqKey="Spurr N">N. Spurr</name></author><author><name sortKey="Stanier, P" uniqKey="Stanier P">P. Stanier</name></author><author><name sortKey="Fisher, E M" uniqKey="Fisher E">E.M. Fisher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dejana, E" uniqKey="Dejana E">E. Dejana</name></author><author><name sortKey="Giampietro, C" uniqKey="Giampietro C">C. Giampietro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Devenport, D" uniqKey="Devenport D">D. Devenport</name></author><author><name sortKey="Fuchs, E" uniqKey="Fuchs E">E. Fuchs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dzamba, B J" uniqKey="Dzamba B">B.J. Dzamba</name></author><author><name sortKey="Jakab, K R" uniqKey="Jakab K">K.R. Jakab</name></author><author><name sortKey="Marsden, M" uniqKey="Marsden M">M. Marsden</name></author><author><name sortKey="Schwartz, M A" uniqKey="Schwartz M">M.A. Schwartz</name></author><author><name sortKey="Desimone, D W" uniqKey="Desimone D">D.W. DeSimone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ewald, A J" uniqKey="Ewald A">A.J. Ewald</name></author><author><name sortKey="Huebner, R J" uniqKey="Huebner R">R.J. Huebner</name></author><author><name sortKey="Palsdottir, H" uniqKey="Palsdottir H">H. Palsdottir</name></author><author><name sortKey="Lee, J K" uniqKey="Lee J">J.K. Lee</name></author><author><name sortKey="Perez, M J" uniqKey="Perez M">M.J. Perez</name></author><author><name sortKey="Jorgens, D M" uniqKey="Jorgens D">D.M. Jorgens</name></author><author><name sortKey="Tauscher, A N" uniqKey="Tauscher A">A.N. Tauscher</name></author><author><name sortKey="Cheung, K J" uniqKey="Cheung K">K.J. Cheung</name></author><author><name sortKey="Werb, Z" uniqKey="Werb Z">Z. Werb</name></author><author><name sortKey="Auer, M" uniqKey="Auer M">M. Auer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Formstone, C J" uniqKey="Formstone C">C.J. Formstone</name></author><author><name sortKey="Mason, I" uniqKey="Mason I">I. Mason</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gaengel, K" uniqKey="Gaengel K">K. Gaengel</name></author><author><name sortKey="Niaudet, C" uniqKey="Niaudet C">C. Niaudet</name></author><author><name sortKey="Hagikura, K" uniqKey="Hagikura K">K. Hagikura</name></author><author><name sortKey="Lavi A, B" uniqKey="Lavi A B">B. Laviña</name></author><author><name sortKey="Muhl, L" uniqKey="Muhl L">L. Muhl</name></author><author><name sortKey="Hofmann, J J" uniqKey="Hofmann J">J.J. Hofmann</name></author><author><name sortKey="Ebarasi, L" uniqKey="Ebarasi L">L. Ebarasi</name></author><author><name sortKey="Nystrom, S" uniqKey="Nystrom S">S. Nyström</name></author><author><name sortKey="Rymo, S" uniqKey="Rymo S">S. Rymo</name></author><author><name sortKey="Chen, L L" uniqKey="Chen L">L.L. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, F B" uniqKey="Gao F">F.B. Gao</name></author><author><name sortKey="Kohwi, M" uniqKey="Kohwi M">M. Kohwi</name></author><author><name sortKey="Brenman, J E" uniqKey="Brenman J">J.E. Brenman</name></author><author><name sortKey="Jan, L Y" uniqKey="Jan L">L.Y. Jan</name></author><author><name sortKey="Jan, Y N" uniqKey="Jan Y">Y.N. Jan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glasco, D M" uniqKey="Glasco D">D.M. Glasco</name></author><author><name sortKey="Sittaramane, V" uniqKey="Sittaramane V">V. Sittaramane</name></author><author><name sortKey="Bryant, W" uniqKey="Bryant W">W. Bryant</name></author><author><name sortKey="Fritzsch, B" uniqKey="Fritzsch B">B. Fritzsch</name></author><author><name sortKey="Sawant, A" uniqKey="Sawant A">A. Sawant</name></author><author><name sortKey="Paudyal, A" uniqKey="Paudyal A">A. Paudyal</name></author><author><name sortKey="Stewart, M" uniqKey="Stewart M">M. Stewart</name></author><author><name sortKey="Andre, P" uniqKey="Andre P">P. Andre</name></author><author><name sortKey="Cadete Vilhais Neto, G" uniqKey="Cadete Vilhais Neto G">G. Cadete Vilhais-Neto</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gomez, G A" uniqKey="Gomez G">G.A. Gomez</name></author><author><name sortKey="Mclachlan, R W" uniqKey="Mclachlan R">R.W. McLachlan</name></author><author><name sortKey="Yap, A S" uniqKey="Yap A">A.S. Yap</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodrich, L V" uniqKey="Goodrich L">L.V. Goodrich</name></author><author><name sortKey="Strutt, D" uniqKey="Strutt D">D. Strutt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gray, R S" uniqKey="Gray R">R.S. Gray</name></author><author><name sortKey="Roszko, I" uniqKey="Roszko I">I. Roszko</name></author><author><name sortKey="Solnica Krezel, L" uniqKey="Solnica Krezel L">L. Solnica-Krezel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hakeda Suzuki, S" uniqKey="Hakeda Suzuki S">S. Hakeda-Suzuki</name></author><author><name sortKey="Berger Muller, S" uniqKey="Berger Muller S">S. Berger-Müller</name></author><author><name sortKey="Tomasi, T" uniqKey="Tomasi T">T. Tomasi</name></author><author><name sortKey="Usui, T" uniqKey="Usui T">T. Usui</name></author><author><name sortKey="Horiuchi, S Y" uniqKey="Horiuchi S">S.Y. Horiuchi</name></author><author><name sortKey="Uemura, T" uniqKey="Uemura T">T. Uemura</name></author><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T. Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halbleib, J M" uniqKey="Halbleib J">J.M. Halbleib</name></author><author><name sortKey="Nelson, W J" uniqKey="Nelson W">W.J. Nelson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iden, S" uniqKey="Iden S">S. Iden</name></author><author><name sortKey="Rehder, D" uniqKey="Rehder D">D. Rehder</name></author><author><name sortKey="August, B" uniqKey="August B">B. August</name></author><author><name sortKey="Suzuki, A" uniqKey="Suzuki A">A. Suzuki</name></author><author><name sortKey="Wolburg Buchholz, K" uniqKey="Wolburg Buchholz K">K. Wolburg-Buchholz</name></author><author><name sortKey="Wolburg, H" uniqKey="Wolburg H">H. Wolburg</name></author><author><name sortKey="Ohno, S" uniqKey="Ohno S">S. Ohno</name></author><author><name sortKey="Behrens, J" uniqKey="Behrens J">J. Behrens</name></author><author><name sortKey="Vestweber, D" uniqKey="Vestweber D">D. Vestweber</name></author><author><name sortKey="Ebnet, K" uniqKey="Ebnet K">K. Ebnet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jakobsson, L" uniqKey="Jakobsson L">L. Jakobsson</name></author><author><name sortKey="Franco, C A" uniqKey="Franco C">C.A. Franco</name></author><author><name sortKey="Bentley, K" uniqKey="Bentley K">K. Bentley</name></author><author><name sortKey="Collins, R T" uniqKey="Collins R">R.T. Collins</name></author><author><name sortKey="Ponsioen, B" uniqKey="Ponsioen B">B. Ponsioen</name></author><author><name sortKey="Aspalter, I M" uniqKey="Aspalter I">I.M. Aspalter</name></author><author><name sortKey="Rosewell, I" uniqKey="Rosewell I">I. Rosewell</name></author><author><name sortKey="Busse, M" uniqKey="Busse M">M. Busse</name></author><author><name sortKey="Thurston, G" uniqKey="Thurston G">G. Thurston</name></author><author><name sortKey="Medvinsky, A" uniqKey="Medvinsky A">A. Medvinsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kametani, Y" uniqKey="Kametani Y">Y. Kametani</name></author><author><name sortKey="Takeichi, M" uniqKey="Takeichi M">M. Takeichi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kibar, Z" uniqKey="Kibar Z">Z. Kibar</name></author><author><name sortKey="Vogan, K J" uniqKey="Vogan K">K.J. Vogan</name></author><author><name sortKey="Groulx, N" uniqKey="Groulx N">N. Groulx</name></author><author><name sortKey="Justice, M J" uniqKey="Justice M">M.J. Justice</name></author><author><name sortKey="Underhill, D A" uniqKey="Underhill D">D.A. Underhill</name></author><author><name sortKey="Gros, P" uniqKey="Gros P">P. Gros</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, R C" uniqKey="Lee R">R.C. Lee</name></author><author><name sortKey="Clandinin, T R" uniqKey="Clandinin T">T.R. Clandinin</name></author><author><name sortKey="Lee, C H" uniqKey="Lee C">C.H. Lee</name></author><author><name sortKey="Chen, P L" uniqKey="Chen P">P.L. Chen</name></author><author><name sortKey="Meinertzhagen, I A" uniqKey="Meinertzhagen I">I.A. Meinertzhagen</name></author><author><name sortKey="Zipursky, S L" uniqKey="Zipursky S">S.L. Zipursky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsubara, D" uniqKey="Matsubara D">D. Matsubara</name></author><author><name sortKey="Horiuchi, S Y" uniqKey="Horiuchi S">S.Y. Horiuchi</name></author><author><name sortKey="Shimono, K" uniqKey="Shimono K">K. Shimono</name></author><author><name sortKey="Usui, T" uniqKey="Usui T">T. Usui</name></author><author><name sortKey="Uemura, T" uniqKey="Uemura T">T. Uemura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Montcouquiol, M" uniqKey="Montcouquiol M">M. Montcouquiol</name></author><author><name sortKey="Rachel, R A" uniqKey="Rachel R">R.A. Rachel</name></author><author><name sortKey="Lanford, P J" uniqKey="Lanford P">P.J. Lanford</name></author><author><name sortKey="Copeland, N G" uniqKey="Copeland N">N.G. Copeland</name></author><author><name sortKey="Jenkins, N A" uniqKey="Jenkins N">N.A. Jenkins</name></author><author><name sortKey="Kelley, M W" uniqKey="Kelley M">M.W. Kelley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muzumdar, M D" uniqKey="Muzumdar M">M.D. Muzumdar</name></author><author><name sortKey="Tasic, B" uniqKey="Tasic B">B. Tasic</name></author><author><name sortKey="Miyamichi, K" uniqKey="Miyamichi K">K. Miyamichi</name></author><author><name sortKey="Li, L" uniqKey="Li L">L. Li</name></author><author><name sortKey="Luo, L" uniqKey="Luo L">L. Luo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nambiar, R M" uniqKey="Nambiar R">R.M. Nambiar</name></author><author><name sortKey="Ignatius, M S" uniqKey="Ignatius M">M.S. Ignatius</name></author><author><name sortKey="Henion, P D" uniqKey="Henion P">P.D. Henion</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nishimura, T" uniqKey="Nishimura T">T. Nishimura</name></author><author><name sortKey="Honda, H" uniqKey="Honda H">H. Honda</name></author><author><name sortKey="Takeichi, M" uniqKey="Takeichi M">M. Takeichi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Norrmen, C" uniqKey="Norrmen C">C. Norrmén</name></author><author><name sortKey="Ivanov, K I" uniqKey="Ivanov K">K.I. Ivanov</name></author><author><name sortKey="Cheng, J" uniqKey="Cheng J">J. Cheng</name></author><author><name sortKey="Zangger, N" uniqKey="Zangger N">N. Zangger</name></author><author><name sortKey="Delorenzi, M" uniqKey="Delorenzi M">M. Delorenzi</name></author><author><name sortKey="Jaquet, M" uniqKey="Jaquet M">M. Jaquet</name></author><author><name sortKey="Miura, N" uniqKey="Miura N">N. Miura</name></author><author><name sortKey="Puolakkainen, P" uniqKey="Puolakkainen P">P. Puolakkainen</name></author><author><name sortKey="Horsley, V" uniqKey="Horsley V">V. Horsley</name></author><author><name sortKey="Hu, J" uniqKey="Hu J">J. Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petrova, T V" uniqKey="Petrova T">T.V. Petrova</name></author><author><name sortKey="M Kinen, T" uniqKey="M Kinen T">T. Mäkinen</name></author><author><name sortKey="M Kel, T P" uniqKey="M Kel T">T.P. Mäkelä</name></author><author><name sortKey="Saarela, J" uniqKey="Saarela J">J. Saarela</name></author><author><name sortKey="Virtanen, I" uniqKey="Virtanen I">I. Virtanen</name></author><author><name sortKey="Ferrell, R E" uniqKey="Ferrell R">R.E. Ferrell</name></author><author><name sortKey="Finegold, D N" uniqKey="Finegold D">D.N. Finegold</name></author><author><name sortKey="Kerjaschki, D" uniqKey="Kerjaschki D">D. Kerjaschki</name></author><author><name sortKey="Yl Herttuala, S" uniqKey="Yl Herttuala S">S. Ylä-Herttuala</name></author><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qu, Y" uniqKey="Qu Y">Y. Qu</name></author><author><name sortKey="Glasco, D M" uniqKey="Glasco D">D.M. Glasco</name></author><author><name sortKey="Zhou, L" uniqKey="Zhou L">L. Zhou</name></author><author><name sortKey="Sawant, A" uniqKey="Sawant A">A. Sawant</name></author><author><name sortKey="Ravni, A" uniqKey="Ravni A">A. Ravni</name></author><author><name sortKey="Fritzsch, B" uniqKey="Fritzsch B">B. Fritzsch</name></author><author><name sortKey="Damrau, C" uniqKey="Damrau C">C. Damrau</name></author><author><name sortKey="Murdoch, J N" uniqKey="Murdoch J">J.N. Murdoch</name></author><author><name sortKey="Evans, S" uniqKey="Evans S">S. Evans</name></author><author><name sortKey="Pfaff, S L" uniqKey="Pfaff S">S.L. Pfaff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabine, A" uniqKey="Sabine A">A. Sabine</name></author><author><name sortKey="Agalarov, Y" uniqKey="Agalarov Y">Y. Agalarov</name></author><author><name sortKey="Maby El Hajjami, H" uniqKey="Maby El Hajjami H">H. Maby-El Hajjami</name></author><author><name sortKey="Jaquet, M" uniqKey="Jaquet M">M. Jaquet</name></author><author><name sortKey="H Gerling, R" uniqKey="H Gerling R">R. Hägerling</name></author><author><name sortKey="Pollmann, C" uniqKey="Pollmann C">C. Pollmann</name></author><author><name sortKey="Bebber, D" uniqKey="Bebber D">D. Bebber</name></author><author><name sortKey="Pfenniger, A" uniqKey="Pfenniger A">A. Pfenniger</name></author><author><name sortKey="Miura, N" uniqKey="Miura N">N. Miura</name></author><author><name sortKey="Dormond, O" uniqKey="Dormond O">O. Dormond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seifert, J R" uniqKey="Seifert J">J.R. Seifert</name></author><author><name sortKey="Mlodzik, M" uniqKey="Mlodzik M">M. Mlodzik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shafer, B" uniqKey="Shafer B">B. Shafer</name></author><author><name sortKey="Onishi, K" uniqKey="Onishi K">K. Onishi</name></author><author><name sortKey="Lo, C" uniqKey="Lo C">C. Lo</name></author><author><name sortKey="Colakoglu, G" uniqKey="Colakoglu G">G. Colakoglu</name></author><author><name sortKey="Zou, Y" uniqKey="Zou Y">Y. Zou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sittaramane, V" uniqKey="Sittaramane V">V. Sittaramane</name></author><author><name sortKey="Sawant, A" uniqKey="Sawant A">A. Sawant</name></author><author><name sortKey="Wolman, M A" uniqKey="Wolman M">M.A. Wolman</name></author><author><name sortKey="Maves, L" uniqKey="Maves L">L. Maves</name></author><author><name sortKey="Halloran, M C" uniqKey="Halloran M">M.C. Halloran</name></author><author><name sortKey="Chandrasekhar, A" uniqKey="Chandrasekhar A">A. Chandrasekhar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strutt, D I" uniqKey="Strutt D">D.I. Strutt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strutt, H" uniqKey="Strutt H">H. Strutt</name></author><author><name sortKey="Warrington, S J" uniqKey="Warrington S">S.J. Warrington</name></author><author><name sortKey="Strutt, D" uniqKey="Strutt D">D. Strutt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tada, M" uniqKey="Tada M">M. Tada</name></author><author><name sortKey="Smith, J C" uniqKey="Smith J">J.C. Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tissir, F" uniqKey="Tissir F">F. Tissir</name></author><author><name sortKey="Bar, I" uniqKey="Bar I">I. Bar</name></author><author><name sortKey="Jossin, Y" uniqKey="Jossin Y">Y. Jossin</name></author><author><name sortKey="De Backer, O" uniqKey="De Backer O">O. De Backer</name></author><author><name sortKey="Goffinet, A M" uniqKey="Goffinet A">A.M. Goffinet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Usui, T" uniqKey="Usui T">T. Usui</name></author><author><name sortKey="Shima, Y" uniqKey="Shima Y">Y. Shima</name></author><author><name sortKey="Shimada, Y" uniqKey="Shimada Y">Y. Shimada</name></author><author><name sortKey="Hirano, S" uniqKey="Hirano S">S. Hirano</name></author><author><name sortKey="Burgess, R W" uniqKey="Burgess R">R.W. Burgess</name></author><author><name sortKey="Schwarz, T L" uniqKey="Schwarz T">T.L. Schwarz</name></author><author><name sortKey="Takeichi, M" uniqKey="Takeichi M">M. Takeichi</name></author><author><name sortKey="Uemura, T" uniqKey="Uemura T">T. Uemura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wada, H" uniqKey="Wada H">H. Wada</name></author><author><name sortKey="Tanaka, H" uniqKey="Tanaka H">H. Tanaka</name></author><author><name sortKey="Nakayama, S" uniqKey="Nakayama S">S. Nakayama</name></author><author><name sortKey="Iwasaki, M" uniqKey="Iwasaki M">M. Iwasaki</name></author><author><name sortKey="Okamoto, H" uniqKey="Okamoto H">H. Okamoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wallingford, J B" uniqKey="Wallingford J">J.B. Wallingford</name></author><author><name sortKey="Rowning, B A" uniqKey="Rowning B">B.A. Rowning</name></author><author><name sortKey="Vogeli, K M" uniqKey="Vogeli K">K.M. Vogeli</name></author><author><name sortKey="Rothb Cher, U" uniqKey="Rothb Cher U">U. Rothbächer</name></author><author><name sortKey="Fraser, S E" uniqKey="Fraser S">S.E. Fraser</name></author><author><name sortKey="Harland, R M" uniqKey="Harland R">R.M. Harland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, L" uniqKey="Zhou L">L. Zhou</name></author><author><name sortKey="Bar, I" uniqKey="Bar I">I. Bar</name></author><author><name sortKey="Achouri, Y" uniqKey="Achouri Y">Y. Achouri</name></author><author><name sortKey="Campbell, K" uniqKey="Campbell K">K. Campbell</name></author><author><name sortKey="De Backer, O" uniqKey="De Backer O">O. De Backer</name></author><author><name sortKey="Hebert, J M" uniqKey="Hebert J">J.M. Hebert</name></author><author><name sortKey="Jones, K" uniqKey="Jones K">K. Jones</name></author><author><name sortKey="Kessaris, N" uniqKey="Kessaris N">N. Kessaris</name></author><author><name sortKey="De Rouvroit, C L" uniqKey="De Rouvroit C">C.L. de Rouvroit</name></author><author><name sortKey="O Eary, D" uniqKey="O Eary D">D. O’Leary</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Belgique</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>New Jersey</li><li>Province du Brabant wallon</li><li>Région wallonne</li><li>État de New York</li></region><settlement><li>Louvain-la-Neuve</li><li>Princeton (New Jersey)</li></settlement><orgName><li>Université catholique de Louvain</li><li>Université de Princeton</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Tatin, Florence" sort="Tatin, Florence" uniqKey="Tatin F" first="Florence" last="Tatin">Florence Tatin</name></noRegion><name sortKey="Makinen, Taija" sort="Makinen, Taija" uniqKey="Makinen T" first="Taija" last="Makinen">Taija Makinen</name><name sortKey="Taddei, Andrea" sort="Taddei, Andrea" uniqKey="Taddei A" first="Andrea" last="Taddei">Andrea Taddei</name><name sortKey="Weston, Anne" sort="Weston, Anne" uniqKey="Weston A" first="Anne" last="Weston">Anne Weston</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Fuchs, Elaine" sort="Fuchs, Elaine" uniqKey="Fuchs E" first="Elaine" last="Fuchs">Elaine Fuchs</name></region><name sortKey="Devenport, Danelle" sort="Devenport, Danelle" uniqKey="Devenport D" first="Danelle" last="Devenport">Danelle Devenport</name></country><country name="Belgique"><region name="Région wallonne"><name sortKey="Tissir, Fadel" sort="Tissir, Fadel" uniqKey="Tissir F" first="Fadel" last="Tissir">Fadel Tissir</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Belgique/explor/OpenAccessBelV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000299 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000299 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Belgique
|area= OpenAccessBelV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3714594
|texte= Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23792146" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a OpenAccessBelV2
| This area was generated with Dilib version V0.6.25. |  |